Inability to mount a CRP response could be explained by low CD4 count of 127 ± 99 μl/ml in their study as compared to 520 ± 236 μl/ml in the current study, as severe immunodeficiency (< 50 μl/ml) is reported to significantly limit inflammatory response, in addition to an increased risk of death [30]. This evidence concerns the gene CRP and Immunodeficiency.