ALB and esophageal squamous cell carcinoma: Lihui Han et.al [19], studied the 206 ESCC patients underwent esophagectomy and found that the patients with low SIS (pretreatment serum Alb≥43.1 g/L and LMR ≥ 2.9) had a better 5-year disease free survival and overall survival than the patients with high SIS (pretreatment serum Alb< 43.1 g/L and LMR < 2.9).