HLA-DQA1 and type 1 diabetes mellitus: Subjects at high risk to develop T1D carry either DQ2.5 haplotype, encoded by DQA1*05:01 and DQB1*02:01 or DQ8 haplotype, encoded by DQA1*03:01 and DQB1*03:02 [4]., whereas the most prominent association of CD is with HLA-DQ2.5 molecules [5].