KDM1A and cancer: Because oleacein was previously shown to exhibit strong suppressive effects against tumor-initiating CSC [10]—a sub-group of cancer cells having an enhanced ability to initiate tumorigenesis and drive therapeutic relapse—and considering the capacity of LSD1 to confer stem-cell-like traits to cancer cells [51,52], it is conceivable that some of the anti-CSC effects of oleacein could occur through LSD1 inhibition.