Another investigation showed that the Campari tomatoes, which contain more β-carotene and lycopene than normal tomatoes, improved diet-induced obesity, dyslipidemia, and hepatosteatosis through gene regulation related to lipogenesis in the model of zebrafish, transcriptionally lowering the expression of sterol regulatory element-binding transcription factor 1 (SREBF1) and increasing the expression of the forkhead box O1 gene (FOXO1) [126]. This evidence concerns the gene SREBF1 and obesity due to melanocortin 4 receptor deficiency.