PTK2 and familial pancreatic carcinoma: Moreover, Src kinase is a mediator of integrin signalling in pancreatic cancer cells 30, and plays an important role in the regulation of several proteins that are frequently deregulated in cancer including focal adhesion kinase (FAK), epidermal growth factor receptor (EGFR), Akt/PI 3‐kinase, and Rho/ROCK signalling.