TGFB1 and neoplasm: Upregulation of ανβ6‐integrins occurs in a variety of tumours, including PDAC, where it has been shown to activate TGF‐β, stimulating tumour cell epithelial‐to‐mesenchymal transition (EMT) and stromal myofibroblast differentiation 66, which has in turn been shown to either promote 67 or restrict tumour growth and progression 68.