TLR4 and cardiovascular disorder: The rs4986790 SNP in TLR4 has been shown to have little evidence of association between the Asp299Gly gene polymorphism and risks for incident myocardial infarction (Zee, Hegener, Gould, & Ridker, 2005) whereas the rs2770150 and rs10759931 SNPs have not been associated with cardiovascular disease.