We found that ZNF384 and ING4 (12p13.31, 5/33, 15%) were frequently amplified in NPC, while SETD2 (3p21.31, 3/33, 9%), BIRC2, and BIRC3 (11q22.2, 3/33, 9%) were frequently deleted (Figure 1). The gene discussed is BIRC3; the disease is nasopharyngeal carcinoma.