KRT8 and posterior cortical atrophy: Although re-expression of chromatin-interacting target genes of rs55958994-associated enhancer such as KRT8, FAIM2, KRT18, and SIPA1 in enhancer-deleted PCa cells did not result in a significant increase of cell growth from our experiments, we cannot exclude their involvement in PCa; it is possible that these genes play roles in PCa progression that are not measured in the assays used in our studies.