KRT8 and cancer: Among the genes having significant changes in transcript levels, eight represented genomic regions with high signals in the Capture-C assay (KRT8, KRT18, and KRT7; Fig. 3B) or positive Capture-C signal (SIPA1, ITGA5, CDH23, FAIM2, and CNTN1; Fig. 3B) and were previously linked to cancer progression; two (CDH23 and SIPA1) of the eight genes are located in trans, while the other six (CNTN1, KRT8, FAIM2, KRT7, ITGA5, and KRT18) are located in cis.