Hisada et al.84 demonstrated that mice with human orthotopic BXPC-3 pancreatic adenocarcinoma tumours had significantly larger clots than control mice in a model of venous thrombosis; furthermore, clots from tumour-bearing mice contained human TF, suggesting the incorporation of circulating tumour-derived microvesicles. Here, TF is linked to pancreatic adenocarcinoma.