We identified genes differentially expressed between the KLF5-KO and control clones based on two criteria: 1) because KLF5 is a transcription factor, the selected differentially expressed genes were downregulated in KLF5-KO cells; 2) differentially expressed genes were components of the pancreatic cancer pathway extracted in KEGG. This evidence concerns the gene KLF5 and pancreatic neoplasm.