KLF5 and neoplasm: We identified differentially expressed microRNAs based on three criteria: 1) because KLF5 is a transcription factor, the selected differentially expressed microRNAs were downregulated in KLF5-knockdown cells; 2) differentially expressed microRNAs inhibited expression of tumor suppressors in the pancreatic cancer pathway extracted in KEGG; 3) interactions between selected differentially expressed microRNAs and target genes such as tumor suppressors and components of the pancreatic cancer pathway were experimentally verified using the miRTarBase (24304892) database.