This effect size in CRP is greater than has been reported in other anxiety disorders (PTSD: SMD=−0.14)24 or MDD (SMD=0.14)6) and is similar to that reported in schizophrenia (SMD=0.45).49 However, the effect size of our meta-analysis was driven by findings in poorer quality studies with small sample sizes. The gene discussed is CRP; the disease is schizophrenia.