CRP and generalized anxiety disorder: The largest study39 (n=5810) examining CRP in GAD examined CRP levels in children from baseline measurement aged 9–16 years to follow-up at age 19–21. This was the only study to examine the longitudinal association between GAD and CRP, and found a bivariate association both cross-sectionally and over time between GAD and elevated CRP; however, this was accounted for by potential covariates, including BMI and medication use.