We observed strongly decreased activation of naive T cells cocultured with IFNγ-pretreated KCs upon blockade of CD54 (Fig. 3c), which is in line with previous results from experiments performed with IFNγ-pretreated KCs and memory T cells.26 This decrease was probably due to a loss of T cell adherence to the IFNγ-pretreated KCs (Fig. S3A, B). Here, IFNG is linked to dry eye syndrome.