TP63 and neoplasm: The expression of circTP63 was positively correlated with TP63 expression (R = 0.719, p < 0.0001) (Supplementary Fig. 2c), suggesting that higher expression of circTP63 was associated with higher expression of TP63. Importantly, increased circTP63 in LUSC tissues was significantly correlated with larger tumor size and higher TNM stage in LUSC patients (Table 1).