The numbers of tumor antigen-specific T cells (Fig. 5c) and IFNγ production (Fig. 5d) in TdLN were determined; (iii) C57BL/6 mice that received vaccination with β-lap-induced dying MC38-OVA cells in the presence of anti-HMGB1Ab were rechallenged with MC38-OVA for evaluation of the antitumor protection (Fig. 5e, f). The gene discussed is IFNG; the disease is neoplasm.