INS and type 2 diabetes mellitus: Of the two loci first reported in an African ancestry GWAS meta-analysis for T2D (the MEDIA Consortium), we found exact replication for INS-IGF2 rs3842770 (p = 1.867 × 10−2, Table 3), but no evidence for replication for HLA-B rs2244020 (rs74995800, p = 0.798).