CYFIP1 and Anxiety: Additionally, because a recent preclinical study demonstrated a parental origin (PO) effect of Cyfip1 haploinsufficiency on hippocampal synaptic transmission, learning, and anxiety-like behavior (Chung et al. 2015) and because a recent clinical study indicated an effect of PO on the distribution of clinical features in 15q11.2 MDS (Burnside-Butler Syndrome) (Davis et al. 2019), we tested whether there would be an effect of PO of Cyfip1 deletion on compulsive-like behavior and PF intake.