TLR7 and systemic lupus erythematosus: Although various cardiac structures have been reported to be affected in mouse models of acute systemic inflammation (Sanghera et al., 2019), the specific phenotype of hemorrhagic myocarditis under such conditions has only been detected in the acute phase of the SLE model induced by application of the Toll-like receptor 7 (TLR-7) agonist Resiquimod (Yokogawa et al., 2014; Hasham et al., 2017).