Moreover, analysis of PRMT3 expression in the 176 pancreatic cancer patients published in The Cancer Genome Atlas (TCGA) database demonstrated that high PRMT3 expression is an unfavorable prognostic factor and is associated with reduced patient survival (Fig. 1d, data derived from https://www.proteinatlas.org/ENSG00000185238-PRMT3/pathology/ tissue/pancreatic+cancer of The Human Protein Atlas) [25]. This evidence concerns the gene PRMT3 and familial pancreatic carcinoma.