RHOA and hepatocellular carcinoma: Pin1 was significantly correlated with the transcript levels of RhoA and RhoC, and their co-overexpressions correlated with metastatic HCC and recurrence of HCC patients, suggesting that Pin1, RhoA and RhoC not only could be used as potential biomarker for predicting development of metastasis after curative resection, but also as potential therapeutic targets to inhibit HCC metastasis.