Similar trends were also observed in the recurrence-free survival analyses of HCC patients, in which patients with downregulations of Pin1, RhoA or RhoC showed a trend of better prognosis for recurrence-free survival when compared with those with overexpressions, and those with co-overexpressions of Pin1+RhoA/RhoC demonstrated a significantly poor recurrence-free survival than those with no co-overexpressions. Here, RHOC is linked to hepatocellular carcinoma.