Regarding vasculogenic mimicry, CDH5 regulates EPH Receptor A2 (EphA2) expression in melanoma cells [87] and, conversely, CDH5 expression was significantly decreased after knockdown of hypoxia-inducible factors (HIF1α or HIF2α) in glioblastoma [88] (Figure 1). The gene discussed is CDH5; the disease is melanoma.