MAPK8 and cancer: This report further describes that an active anti-cancer compound present in Ft-3 is F-6 (12,15-epoxy-13,14-dimethyleicosa-12,14-dienoic acid), which prevents cancer cell proliferation (e.g., blocking JNK pathway), induces apoptotic cell death (e.g., suppressing Akt pathway) and prevents cell recovery, in a dose-dependent manner.