However, recent work has shown that ovarian cancer cells are capable of hematogenous metastasis, using a parabiosis model to demonstrate that hematogenous metastasis is driven by ErbB3-Neuroegulin1 signaling, and is a key contributor to the high percentages of omental metastasis observed in ovarian cancer [4,17,18]. Here, ERBB3 is linked to ovarian carcinoma.