Suberoylanilide hydroxamic acid (SAHA), a histone deacetylase (HDAC) inhibitor used in the treatment of cutaneous T-cell lymphoma, was administered in combination with EGCG, a DNA methyltransferase (DNMT) inhibitor, against MDA-MB-231 and MDA-MB-157 (triple-negative) breast cancer cell lines. The gene discussed is DNMT1; the disease is breast cancer.