SLC6A3 and bipolar disorder: Given that DAT1 plays an important role in affective and behavioral regulation, it is not surprising that several studies on clinical samples have reported significant associations of DAT with various developmental psychopathologies such as the attention-deficit/hyperactivity disorder (ADHD; [29,30,31]), conduct disorder [32], post-traumatic stress disorder [33], oppositional defiant disorder [34], autism spectrum disorder [35], and pediatric bipolar disorder [36].