Fibroblasts lacking mitofusin proteins produce less IFN and pro‐inflammatory cytokines upon viral infection.72, 73 Small molecules, such as mitochondrial division inhibitor 1 (Mdivi1) that inhibits Drp1 activity, have been developed.74 Hence, the effects of these agents on different hepatitis viruses are interesting be investigated. Here, IFNA1 is linked to viral infectious disease.