TARDBP and Alzheimer disease: Likewise, the syndrome of CBS is associated with pathologies other than CBD including PSPd, frontotemporal lobar degeneration with ubiquitin- and TDP-43-positive inclusions (FTLD-TDP), AD, Pick’s disease, Lewy body disease, as well as mutations in the microtubule-associated protein tau and progranulin genes [30, 31].