There were no differences between CF-AOC or CF-PLC and controls in pretreatment baseline diameter (p = 0.463 and p = 0.077, respectively), peak diameter (p = 0.688 and p = 0.126), or absolute change in diameter (p = 0.434 and p = 0.753); however, TTP was lower in controls versus both CF-AOC (p = 0.008) and CF-PLC (p = 0.024). The gene discussed is HSPG2; the disease is cystic fibrosis.