When a chemopreventive agent is given to the organism, pharmacological boosting of the Nrf2 activity occurs to protect the organism from oxidative damage that may occur due to toxic metabolites or diseases such as cancer, mitochondrial damage, or ethanol-induced lesions (Talalay et al., 2003; Dong et al., 2008; He and Ma, 2012). This evidence concerns the gene NFE2L2 and cancer.