IL6 and rheumatoid arthritis: Plasma levels of IL-6 were significantly higher at RA onset (48.4 ± 56.5 pg/ml) than in RA in sustained remission (3.4 ± 7.9 pg/ml; p < 0.001), whereas IL-1RA plasma levels were not statistically different between naïve RA (647.3 ± 397.9 pg/ml) and RA in sustained remission (464.4 ± 217.4 pg/ml; p = 0.07).