The chi-square in the models to predict outcome using the GWTG-HF risk score only, the GWTG-HF risk score and NT-proBNP, and the GWTG-HF risk score, NT-proBNP, and RVSP significantly improved adding these two parameters to the GWTG-HF risk score (Fig. 5B). This evidence concerns the gene NPPB and hydrops fetalis.