Functionally, WWP1 has been postulated to function as an oncogenic factor by regulating the stability of several cancer-related proteins, such as p53, p63, KLF2, JunB, HER4, and KLF5, and its dysregulation has been implicated in cancers, infectious diseases, neurological diseases, and ageing9,10,15. The gene discussed is ERBB4; the disease is cancer.