Notably, miR-493-3p and MEG3 expression was inhibited in a more significant manner in HCC tumors: 0.291 versus 0.858 (p = 0.0104) and 0.127 versus 0.887 (p < 0.0001), respectively (Supplementary Fig. 4). The gene discussed is MEG3; the disease is hepatocellular carcinoma.