TARDBP and dementia: The authors examined 47 post-mortem spinal cord samples of a wide variety of ALS cases, such as sALS (n = 23), fALS without mutations in SOD1, TDP-43 and FUS (n = 5), ALS with dementia (n = 5) and fALS with G298S mutation in TDP-43 (n = 21) [12].