Our non-causal findings are in line with recent MR studies among European populations on IHD that used UGT1A1 and SLCO1B1, which are known to be bilirubin metabolism genes, and suggested that bilirubin is not causally associated with IHD risk [7] (Supplementary Material 4). The gene discussed is SLCO1B1; the disease is myocardial ischemia.