BCL2 and medulloblastoma: To further elucidate simvastatin-induced cell death in medulloblastoma cells, we investigated the expression of anti- and pro-apoptotic proteins in the Bcl-2 family [Mcl-1, Bcl-xl, Bcl-2 (anti-apoptotic) and Bax (pro-apoptotic) at 24 h, 48 h, and 72 h].