Moreover, expression of the Cdh1 Asp187Gly mutant in Cdh1−/− cultured cortical cells failed to induce cell cycle arrest, as reveals the enlargement of the S phase length, a feature known to result in prenatal microcephaly (Delgado‐Esteban et al. 2013; Eguren et al. 2013) as observed in the patient harboring the 560A>G missense mutation. Here, CDH1 is linked to microcephaly.