Though the aforementioned studies are consistent with the role of WT p53 as a tumor suppressor, a recent paper described a confounding finding, in which WT p53 seems to promote tumor-promoting functions of CAFs, suggesting that WT p53 may be implicated in the ‘education’ of stromal cells in the microenvironment (Arandkar et al., 2018). The gene discussed is TP53; the disease is neoplasm.