Because we found that GLK overexpression induces ROR-γt Ser-489 phosphorylation and the AhR–ROR-γt complex (18), we further studied whether ROR-γt Ser-489 phosphorylation and the AhR–ROR-γt complex occur in T cells of human patients with SLE using immunoblotting and in situ PLA. The gene discussed is AHR; the disease is systemic lupus erythematosus.