MAP3K1 and central nervous system cancer: Moreover, coexpression of TRIB2 and MAP3K1 (TRIB2High/MAP3K1High) was identified in 52 of all 91 samples (57.14%) and showed statistical significance (Pearson's χ2 = 34.12, P < 0.01), indicating that high expression of TRIB2 and MAP3K1 was markedly associated with the histological classification in glioma (Table 3).