Recently, patients carrying deletions or missense point mutations in the NR2F1 locus have also been diagnosed with optic atrophy associated with developmental delay and intellectual disability (Al‐Kateb et al, 2013; Bosch et al, 2014; Chen et al, 2016; Kaiwar et al, 2017). Here, NR2F1 is linked to Leber hereditary optic neuropathy.