GPRC5A and cancer: Even with the rapid development of new technologies and our deeper understanding of molecular biology, the exact mechanisms of GC development remain unclear, which greatly limits our ability to treat GC.1 Non‐coding RNAs become dysregulated during all processes involved in carcinogenesis and thus represent promising biomarkers for use in the diagnosis and treatment of cancer.17 In this study, hsa_circ_006100 was identified as an oncogene that promotes GC cell proliferation and metastasis via regulation of miR‐195/GPRC5A signalling.