These observations were explained in various cancers by a mechanism in which the presence of MHC‐I and a membrane‐associated form of FasL on the TDE surface could suppress T‐cell responses by inducing apoptosis,116, 117 as indicated by the ability of anti‐Fas or anti‐MHC class I antibodies to block this effect.116, 147. Here, FASLG is linked to cancer.