H19 and lung adenocarcinoma: For investigation into the effects of CDH1 and lncRNA H19 on the EMT process, we further performed scratch test and Transwell assay to ascertain whether silencing of lncRNA H19, overexpression of CDH1 or inhibition of CDH1 methylation could affect migration and invasion of lung adenocarcinoma cells (Figure 5A,B,C,D).