Neuraminidase treatment or knockdown of ST6Gal1 enhances cell adhesion to galectin‐1, ‐3, ‐8, and laminin, and inhibits lymphoma cell invasion.24, 25 Marked enhancement of cell adhesion to galectins or extracellular matrix may inhibit the motility or invasion of lymphoma cells into the extracellular space. This evidence concerns the gene LAMB2 and lymphoma.