While some studies report that CRC patients having a high expression of EZH2 show a lower overall disease-free survival (DFS) (Liu et al. 2015; He et al. 2014; Mimori et al. 2005), other reports describe that a high expression of EZH2 in CRC patients is correlated with an improved relapse-free survival (Benard et al. 2014; Fluge et al. 2009; Takawa et al. 2011). Here, EZH2 is linked to colorectal carcinoma.