According to previous studies, IL-6, IL-8, and IFN-γ represent the lung immune to response to adenovirus infection (17, 20), and IL-1α, IL-2, IL-4, IL-5, IL-6, IL-8, IL-17A, IFN-γ, and TNF-α are the major inflammatory cytokines induced by M. pneumoniae infection (17, 21–23). The gene discussed is CXCL8; the disease is adenoviridae infectious disease.