Because there is no Ab to specifically detect IL-35 heterodimer, we analyzed IL-35 expression in DLBCL tissues (n = 75) by staining serial tissue sections with 2G4H6 mouse anti-EBI3 mAb and with goat polyclonal anti-p35 Abs or rabbit anti-p35 mAb (Figure 3). This evidence concerns the gene EBI3 and diffuse large B-cell lymphoma.