EBI3 and diffuse large B-cell lymphoma: In contrast, detection of p28 (IL27), the alternative partner for EBI3 to form IL-27 (EBI3/p28 heterodimer), resulted in low signals that were not increased in DLBCL compared to Burkitt lymphoma (Figure 1C), which was consistent with our previous lack of p28 detection by immunohistochemistry in tumor cells of DLBCL (26).