TP53 and esophageal squamous cell carcinoma: There were 8 (40%) males withTP53 gene mutations and 12 (60%) females.TP53 mutations were found in 22.9% of esophageal SCCs and 14.3% of esophageal ACs in a study done by Zhenget al. 35 here the ratio was (34.9% vs. 57.1%) respectively.