TP53 and carcinoma of esophagus: Shiet al.36 in Henan province, China showed that the p53 mutations were detected in 30 out of 43 (70%) SCC cases but in this study it represents 16 out of 43 (37.2%); this difference can be attributed to different factors e.g. geographical zone differences or type of exons studied as China has a high-incidence of esophageal carcinoma.