A number of other RAAGs found to be significantly associated with CKD progression could be assigned to the broader context of cell adhesion and extracellular matrix remodeling including VCAN, MMP7, ITGB2, CLDN1, TSPAN1, TPBG, or CGNL1 based on information from GO terms and scientific literature. This evidence concerns the gene TSPAN1 and chronic kidney disease.